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Home > Products > API > Paclitaxel API pure Synthesis paclitaxel 99% CAS: 33069-62-4

Paclitaxel API pure Synthesis paclitaxel 99% CAS: 33069-62-4

Basic Info

Model No.: Top Grade

Product Description

Paclitaxel API pure Synthesis paclitaxel 99% CAS: 33069-62-4

Product Description

Name:Paclitaxel API pure Synthesis paclitaxel 99% CAS: 33069-62-4

CAS NO.: 33069-62-4

Appearance:White crystalline powder

 

Standard: USP 32

Natrual Paclitaxel 99.5% HPLC 

Natural Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent.

Specification

Tests

Standards

Results

Appearance

 white powder 

Wcrystalline powder.hite, 

Identification

A:IR absorption

Complies

Complies

B:UV absorption

Complies

Complies

C:TLC

Complies

Complies

Melting point

168~172°C

169.0~170.9°C

Water

Not more than0.5%

0.08%

Related substance

ImpurityJ(chloroacetanilide)not more than 10 ppm 

2ppm

Impurity K(4-aminophenol)not more than 50 ppm

15 ppm

Impurity F(4-nitrophenol)not more than 0.05%

Not detected

any other impurity not more than 0.05%

0.01%

Total of other impurities not more than 0.1%

0.02%

Residue on ignition

Not more than 0.1%

0.05%

Chloride

Not more than 0.014%

Less than 0.014%

Sulfate

Not more than 0.02%

Less than 0.02%

Sulfide

Conforms

Conforms

Heavy metals

Not more than 0.001%

Less than 0.001%

Free p-aminophenol

Not more than 0.005%

Less than 0.005%

Limit of P-chloroacetanilide

Not more than 0.001%

Less than 0.001%

Readily carbonizable substances

Conforms

Conforms

Residual solvents

Residual content of acetic acid is limited

 by the test of loss on dryingnot more than0.5%

0.08%

Assay(anhydrous basis)

99.0~101.0%

99.6%

Conclusion:   Complies with USP34/ BP2011

Packing and Shipping

1kg with double plastic container inside/Aluminum foil bag; 
25kg with double plastic container inside/Fiber drum outside.Or as your request.

Store in a well-closed container away from moisture.

Shipped within 3 days after get the payment.

Function and Application

 

1. Paclitaxel is a mitotic inhibitor drup used in the treatment of cancer.
2. Isolated the compound from the bark of the Pacific yew tree, Taxus brevifolia, and noted its antitumor activity in a broad range of rodent tumors.
3. Paclitaxel has since become an effective tool of doctors who treat patients with lung, ovarian, breast cancer, and advanced forms of Kaposi's sarcoma.  
4. Paclitaxel is also used for the prevention of restenosis (recurrent narrowing) of coronary stents; locally delivered to the wall of the coronary artery, a paclitaxel coating limits the growth of neointima (scar tissue) within stents. 

OMM


   

 

 Xi’an Wharton Bio-Tech Co.,Ltd  is a national key high-tech enter prise,which mainly specializes in the R&D,operation and production of pharmaceutical APIs and intermediates.Our company is situated in E&T development zone,xi’an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.we have GMP standard workshop and complete equipment.the superior product qualityis guaranteed by 300,000 level air-conditioning clear system within purification drying and packing procedures.we have 2 sales department over 30 people and sell our products all over the world.we also have strong professional research and development team,talented personnel and completely equipped laboratory for quality controlling.Various detection device is equipped in Wharton such as HPLC,GS,Spectrophotometer,AAS,Polarimeter,Auto titrators,BOD Incubators,COD Incubators,Melting point apparatus and so on.

Our Service

 

---------------------------------------------------------------------------------------------------------------------------------------------------------------------1. All inquiries will be replied within 12 hours.

 

2. Dedication to quality, supply & service.

 

3. Strictly on selecting raw materials.

 

4. OEM/ODM Available.

 

5. Reasonable & competitive price, fast lead time.

 

6. Sample is available for your evaluation & Formulation development.

 

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

 

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

 

9. After-Sale Service:

 

1) International Authorized Third-Party Test For The Products You Demand.

 

2) 30 Days Warranty of quality of goods. 

 

Our Advantage

 

 

 FAQ ------------------------------------------------------------------------------------------------------------------------

 

1.Are you a manufacturer or trade company?

 

We are a professional manufacturer.

 

2.What products your company specialize in?
We specialize in Vitamin B12(Cyanocobalamin), Coenzyme Q10 , Nicotinamide Riboside , Scopolamine Butylbromide , Vitamin B1 ,Vitamin B6 , Vitamin B9(folic acid) , Vitamin k2 mk7 ,Hyaluronic Acid.

 

3.What’s your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount.

 

4.What’s the warranty service do you offer?
We offer 24 month warranty for all our products.

 

 5.How do you ensure monthhigh quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

 6.How do you ship the order normally?

For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, includingDHL,FEDEX,UPS,TXT,EMS,ARAMES and so on.

 

  Send your Inquiry Details in the Below, Click "   Send " Now!

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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