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Home > Products > API > Supply Top quality Irinotecan API/Irinotecan HCl

Supply Top quality Irinotecan API/Irinotecan HCl

Basic Info

Model No.: Wharton

Product Description

Supply Top quality Irinotecan API/Irinotecan HCL

 

 

Irinotecan Hydrochloride Trihydrate (CAS Number:136572-09-3)

 

Chemical formula:  C33H45ClN4O9

Synonyms: [1,4'-Bipiperidine]-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-ylester, monohydrochloride, trihydrate,( 54591309,S)-;Irinotecanhydrochloridehydrate.

Molecular weight: 677.1

 

Chemical/ Physical Properties: Yellowish to yellow crystalline powder. Slightly soluble in water, ethanol and chloroform, insoluble in acetone.

 

Irinotecan Hcl Test standard:

Items

Specifications

Appearance

Pale yellow or yellow crystalline powder,odorless

Identification

a) IR

IR chromatograph Conforms to the characteristic peak of  R.S.

b) HPLC

The retention time of the majorpeak in the chromatogram 

Conforms to  the characteristicpeak of  R.S.

Specific rotation

+61.0º~+69.0º

Water

7.0%~9.0%

Residue on ignition

Not more than 0.1%

Heavy metal

Not more than 10ppm

Irinotecan Hydrochloride R-enantiomer

Not more than 0.15%

Camptothecin

Not more than 0.15%

10-Hydroxycamptothecin

Not more than 0.15%

 7-Ethyl-10-hydroxycamptothecin

Not more than 0.15%

7,11-Diethyl-10-hydroxycamptothecin

Not more than 0.15%

7-Ethyl camptothecin

Not more than 0.15%

7-Desethylirinotecan

Not more than 0.15%

11-Ethyl camptothecin

Not more than 0.15%

Any unknown individual impurity

Not more than 0.10%

Total impurities

Not more than 0.50%

Assay[calculated on anhydrous basis]

98.0%~102.0%

Residue solvents

n-Hexane

Not more than 290ppm

Methanol

Not more than 3000ppm

Acetone

Not more than 5000ppm

Pyridine

Not more than 200ppm

Dichloromethane

Not more than 600ppm

Ethanol

Not more than 5000ppm

Staphylococcus aureus, pseudomonas

 aeruginosa, salmonella species, and 

Escherchia coli

Absence

Bacterial ensotoxin

Not more than 0.556 EU/mg

Microbial limits

Total aerobic microbial

Not more than 1000cfu/g

Molds and yeasts

Not more than 100cfu/g

 

Irinotecan Hcl Usage:  Mainly used in the treatment of digestive system tumors such as gastric cancer, colon cancer, rectal cancer, lung cancer and so on, also used to treat leukemia, hydatidiform mole and chorionic carcinoma. The stand for kang is a through chemical structure modification of natural derivative of camptothecin. It's curative effect, less toxic and side effect of new cancer drugs, mainly used in the treatment of lung cancer, colorectal cancer, gastric cancer, cervical cancer, ovarian cancer and other cancers

Packaging & Shipping

 
Our Services

1. All inquiries will be replied within 12 hours.

 

2. Dedication to quality, supply & service.

 

3. Strictly on selecting raw materials.

 

4. OEM/ODM Available.

 

5. Reasonable & competitive price, fast lead time.

 

6. Sample is available for your evaluation & Formulation development.

 

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

 

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

 

9. After-Sale Service:

 

1) International Authorized Third-Party Test For The Products You Demand.

 

2) 30 Days Warranty of quality of goods. 

 

Our Advantage :

 

Company Information

Xi’an Wharton Bio-Tech Co.,Ltd  is a national key high-tech enter prise,which mainly specializes in the R&D,operation and production of pharmaceutical APIs and intermediates.Our company is situated in E&T development zone,xi’an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.we have GMP standard workshop and complete equipment.the superior product qualityis guaranteed by 300,000 level air-conditioning clear system within purification drying and packing procedures.we have 2 sales department over 30 people and sell our products all over the world.we also have strong professional research and development team,talented personnel and completely equipped laboratory for quality controlling.Various detection device is equipped in Wharton such as HPLC,GS,Spectrophotometer,AAS,Polarimeter,Auto titrators,BOD Incubators,COD Incubators,Melting point apparatus and so on.

 
FAQ

1.Are you a manufacturer or trade company?

 

We are a professional manufacturer.

 

2.What products your company specialize in?
We specialize in Vitamin B12(Cyanocobalamin), Coenzyme Q10 , Nicotinamide Riboside , Scopolamine Butylbromide , Vitamin B1 ,Vitamin B6 , Vitamin B9(folic acid) , Vitamin k2 mk7 ,Hyaluronic Acid.

 

3.What’s your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount.

 

4.What’s the warranty service do you offer?
We offer 24 month warranty for all our products.

 

 5.How do you ensure monthhigh quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

 6.How do you ship the order normally?

For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, includingDHL,FEDEX,UPS,TXT,EMS,ARAMES and so on.

How to contact us

 

 

 

Send your Inquiry Details in the Below, Click "   Send " Now!

 

 

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