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Home > Products > API > Top quality Terbinafine Hydrochloride/Terbinafine Hcl/CAS No.78628-80-5

Top quality Terbinafine Hydrochloride/Terbinafine Hcl/CAS No.78628-80-5

Basic Info

Model No.: Top Grade

Product Description

Top quality Terbinafine Hydrochloride/Terbinafine Hcl/CAS No.78628-80-5

Product Description

Product Name: Terbinafine HCL

Purity: 98%min

Appearance: White crystalline powder

CAS No.: 78628-80-5

EINECS: 245-385-8

Molecular formula: C21H25NHCl

Molecular weight: 327.9

Specification

Items

Specifications

Results

Appearance

White or almost white powder

White powder

Solubility

Practically insoluble in water and in aceton, soluble in ethanol and in methanol

Complies

Identification

 

 

A: IR

The infrared absorption spectrum exhibits maximum only at the same wavelengths as that of the standard sample

Complies

B:

It gives reaction of chlorides

Complies

 

Impurity A NMT 0.1%

0.00%

 

Impurity B NMT 0.1%

0.01%

 

Impurity C NMT 0.1%

0.02%

 

Impurity D NMT 0.1%

0.02%

 

Any other impurity NMT0.1%

0.05%

 

Total of impurity NMT 0.3%

0.15%

Loss on drying

NMT0.5%

0.15%

Sulphated ash

NMT0.1%

0.02%

Assay

99%~101% (dried substance )

99.85%

Function and Application

Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.

 

1. Terbinafine is mainly effective on the dermatophyte group of fungi.


2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.


3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. Alternatives to oral administration have been studied.


4. Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.

Packing and Storage

1kg with double plastic container inside/Aluminum foil bag ;
25kg with double plastic container inside/Fiber drum outside.Or as your request.
Shipped in 3 days after payment.
1.Stored in a cool and dry well-closed container and in ventilated area.
2.kept away from moisture and strong light or high temperature.
3.Two years under well storage situation and stored away from direct sun light.

OMM


   

 

 Xi’an Wharton Bio-Tech Co.,Ltd  is a national key high-tech enter prise,which mainly specializes in the R&D,operation and production of pharmaceutical APIs and intermediates.Our company is situated in E&T development zone,xi’an city shaanxi,it is easy of access.Our company has independent R&D center,raw material synthesis workshop,has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.we have GMP standard workshop and complete equipment.the superior product qualityis guaranteed by 300,000 level air-conditioning clear system within purification drying and packing procedures.we have 2 sales department over 30 people and sell our products all over the world.we also have strong professional research and development team,talented personnel and completely equipped laboratory for quality controlling.Various detection device is equipped in Wharton such as HPLC,GS,Spectrophotometer,AAS,Polarimeter,Auto titrators,BOD Incubators,COD Incubators,Melting point apparatus and so on.

Our Service

 

---------------------------------------------------------------------------------------------------------------------------------------------------------------------1. All inquiries will be replied within 12 hours.

 

2. Dedication to quality, supply & service.

 

3. Strictly on selecting raw materials.

 

4. OEM/ODM Available.

 

5. Reasonable & competitive price, fast lead time.

 

6. Sample is available for your evaluation & Formulation development.

 

7. Faster delivery:Sample order in stock and 3-7 days for bulk production.

 

8.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder

 

9. After-Sale Service:

 

1) International Authorized Third-Party Test For The Products You Demand.

 

2) 30 Days Warranty of quality of goods. 

 

Our Advantage

 

 

 FAQ ------------------------------------------------------------------------------------------------------------------------

 

1.Are you a manufacturer or trade company?

 

We are a professional manufacturer.

 

2.What products your company specialize in?
We specialize in Vitamin B12(Cyanocobalamin), Coenzyme Q10 , Nicotinamide Riboside , Scopolamine Butylbromide , Vitamin B1 ,Vitamin B6 , Vitamin B9(folic acid) , Vitamin k2 mk7 ,Hyaluronic Acid.

 

3.What’s your payment terms?
Standard terms: T/T in advance and Western Union.
Also L/C at sight is acceptable for large amount.

 

4.What’s the warranty service do you offer?
We offer 24 month warranty for all our products.

 

 5.How do you ensure monthhigh quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

 6.How do you ship the order normally?

For large qty order,ship the goods by sea.
For small qty order, by air or express. We supply optional express for you, includingDHL,FEDEX,UPS,TXT,EMS,ARAMES and so on.

 

  Send your Inquiry Details in the Below, Click "   Send " Now!

 

 

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